Therapeutic Uses Indications

Therapeutic Uses Indications

As based on the specific (medical and physiological) effects of ozone, we find the indications listed in the following table:

Indications

Underlying effects

1. Arteral Circulatory disorders

O2-release effect
Activation of RBC metabolism

2. External Ulcera and skin lesions

Disinfection
Wound cleansing
improved wound healing

3. Pathological intestinal conditions

    colitis

    proktitis

    fistulas

Disinfection
Immunoactivation
antiinflammatory processes

4. Infections and virus caused diseases

Immunomodulation

5. Additive therapy in carcinogenic conditions

Immunoactiviation

6. Geriartric conditions

O2-release effect
Immuno- and enzymeactiviation

7. Rheumatic diseases

    inflammatory conditions

    degenerative conditions

antiinflammatory processes
Activation of antioxidative capacity
Immunomodulation

8. Dentistry

Disinfection
Wound cleansing
improved wound healing

Applikation

Indication

Mechanism of action

1. Systemic applications


Major autohemotherapy as an extracorporeal blood treatment and intravenous reinfusion of the patients own blood.

Arterial circulatory disorders

Activation of red blood cell metabolism with increase of 2,3-DPG and ATP plus resultant improvement in O2-release


Infections, Immunoactivation, additive therapy in carcinoma patients,
geriatric field

Activation of immunocompetent cells with release of cytokins, such as Interferons and Interleukins.


Rheumatic arthritis

Modulation of immune system with increase of IFN-ß, TGF-ß

Increase of the antioxidative capacity by activation of SOD, GSHPx, Catalase ...


Rectal insufflation

Arterial circulatory disorders (stage II)
general immunoactivation,
adjuvant cancer therapy.
Hepatitis A,B,C

see above


Minor autohemotherapy as extracorporeal blood treatment and intramuscular injection.

Allergies, acne, furunculosis.
Adjuvant cancer therapy.

Non-specific activation of the immune-system
general stimulation.

2. Topical application


Transcutanous gas bath in ozone resistant plastic bag

Ulcus cruris;
dermatosis,
fungus infections

Microbicidal effect of ozone:
baktericidal, fungicidal, virus inactivating effect


Low-pressure application with suction cup or in plastic boot

Decubitus,
diabetic gangrene
badly healing wounds,
fistulas, radiation damage

wound cleansing
improved wound healing
immunoactivation (TGF-ß)


Rectal Insuffylation

Proctitis;
colitis

Antiinflammatory effect,
better O2-supply,
wound healing effect

Vaginal Insufflation

e.g. candida infection

fungicidal effect


Intraarticular injection (mainly knee and shoulder)

Rheumatoid arthritis,
Knee arthrosis,
Gonarthrosis;
traumatic knee disorders

antiflammatory effect,
activation of SOD as radical scavanger,
activation of immunocompetent and cartilage cells,
release of TGF-ß

"Blistering" paravertebral injection and intramuscular injections (in combination with tonanalgetic treatment)

Myotraumatic syndrome,
myogelosis,
triggerpoints

Activation of cell metabolism,
ATP-increase
Activation of antioxidants


Ozonized water as spray or compresses

fresh lesions, burns,
fungus infections,
herpes

Wound cleansing,
antiinflammatory effects,
activation of cell metabolism,
immunoactivation (TGF-ß)

dropwise application

otitis

immunoactivation (TGF-ß)


Ozonized water as spray,
or rinsing with O3-water

Dental medicine:
following tooth extractions,
buccal infections (e.g. candida) apthae,
parodontosis

Disinfection,
wound healing effect, see above.


Topical treatment

Fungus infections,
bacterialinfections,
burns, skin lesions.

fungicidal and baktericidal effect,
wound healing.

Contraindications

"Contraapplications"

Hyperthyreosis
Glucose-6-Phosphate-Dehydrogenase-deficiency (favism)

direct gasinjections:
intravenous injections: strictly prohibited.
intraarterial injections (arteria femoralis): not rejected on very special conditions

 

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